Background. The middle ear is an air-filled lacuna in the temporal bone. Inhaled anesthetic agents increase the pressure of this\nlacuna. Therefore, attention must be paid in choosing not only anesthetic agents but also anesthetic method. Aim. This study\ncompared the effects of high-flow total intravenous anesthesia (TIVA) and low- and high-flow desflurane anesthesia on middle ear\npressure. Study Design. Randomized prospective double-blind study. Methods. In this retrospective double-blind study, 90 patients\n(20ââ?¬â??65 years old) scheduled to undergo elective thyroidectomies were divided into three randomized anesthesia groups: high-flow\ndesflurane (Group I), low-flow desflurane (Group II), and high-flow TIVA (propofol, remifentanil) (Group III). The hemodynamic\nand respiratory parameters and tympanometry were measured before induction (
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